Technology
R&D

MicruX has extensive experience in the use of the most innovative technologies for the development of novel products in the microfluidic and electrochemistry field.

» Lab-on-a-Chip » Capillary electrophoresis» Electrochemistry» Biosensor» Photolithography» Wet etching» Thermal bonding» Metal deposition

 

» Lab-on-a-Chip

The current trend for the simplification, miniaturization and automation of the analytical systems have given the named Lab-on-a-Chip (LOC) or Micro Total Analysis Systems (µTAS).

Lab-on-a-Chip technology pretends to integrate the main steps of an analytical process (mix, reactions, injection, separations, detection, etc...) carried out in a laboratory in a very small device [+].

Microfluidics, the manipulation of fluids in channels with dimensions of tens of micrometres, can be considered a part of the Lab-on-a-Chip technology that has developed continuously and became a distinct new field.

These novel devices offer high speed, great versatility, high throughput, low cost, performance of parallel assays and negligible consumption of reagents/sample and waste generation.

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» Capillary electrophoresis

Capillary electrophoresis is a powerful analytical technique used to separate ionic species with different migration times. It can be done due to the different charge to mass ratio of these species in a conductive liquid medium under the influence of an electric field [+].

Capillary electrophoresis

This separation technique is useful to separate small organic and inorganic ions as well as biomolecules such as proteins and nucleic acids (RNA and DNA).

Microfluidic electrophoresis chips can be considered an evolution through the miniaturization of the traditional capillary electrophoresis technique. Thus, these novel devices are the first stage to get a “true” Lab-on-a-Chip (LOC) in which would be integrated all the steps of an analytical process.

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» Electrochemistry

Electrochemical techniques are based on oxidation and reduction reactions (electron transfer reactions) which take place on an electrode surface [+].

Electrochemistry

Electrochemical detection systems show several important features such as selectivity, sensitivity, low cost, portability and compatibility with the microfabrication techniques.

These systems have been widely used in micro- and nanotechnology. Moreover, electrodes are a very useful tool in the construction of (bio)sensors.

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» Biosensor

A biosensor is an analytical device for the detection of an analyte that combines a biological component with a physicochemical detector component [+].

Therefore, a biosensor consists of three main parts:

» A biological sensing element (biological material such as microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc).

» A transducer (electrochemical, optical, piezoelectric detectors, etc...) that transforms the signal resulting from the interaction of the analyte with the biological element into an easily measurable signal.

» Associated electronics or signal processors to display the results in a user-friendly way.

In case of using an electrochemical transducer, the biological recognition element can be immobilized in the electrode surface in order to get the biosensor.

Biosensor

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» Photolithography

Photolithography is a process used in microfabrication to selectively remove parts of a thin-film (or the bulk of a substrate). It uses light to transfer a pattern from a photomask to a light-sensitive chemical on the substrate. These wafers are made on different materials: glass, silicon, quartz, polymers and also metals.

Photolithography (also known as "microlitography" or "nanolithography") works similarly to traditional lithography used in printing jobs. It also shares some fundamental principles with photography [+].

This technology is useful in the manufacture of microfluidic devices as well as thin-film electrodes and microelectrodes.

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» Wet etching

Wet etching is used in microfabrication to chemically remove layers from the surface of a wafer during manufacturing. The selection of the solution employed for this process is critically important [+].

When glass substrates are used, hydrofluoric acid is the solution employed to remove the selected parts of the wafer.

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» Thermal bonding

This process is used to bond two surfaces, usually the same material, by applying pressure and temperature close to glass transition temperature (Tg) of the material [+].

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» Metal deposition

Thin-film metal deposition is widely used in microfabrication. Different technologies such as sputtering or chemical vapor deposition (CVD) can be used for thin-film deposition on several substrates (silicon, glass, polymers...).

The combination of photolithographic processes, metal deposition and lift-off enable the fabrication of electrodes and microelectrodes with high precision and resolution for using in microfluidic devices and sensors.

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News & Events
June 12, 2017
New Products: External Electrodes & Platform [+].
April 10, 2017
microTAS 2017 - Get a Free Full Registration!!! [+].
March 13, 2017
Updated MicruX' Catalogue 2017 [+].
March 01, 2017
Events: First European BioSensor Symposium (Potsdam, Germany, 20 - 23 March 2017) [+].
February 06, 2017
Microfluidic Lab Practice Packs - Special Offers [+].
January 30, 2017
New available position: International Sales Technician [+].
January 23, 2017
New available position: Electronic Engineer [+].
September 26, 2016
Events: MicroTAS 2016 (Dublin, Ireland, 9 - 13 October 2016) [+].
September 13, 2016
Events: PRiME 2016 (Honolulu, Hawaii, USA, 2 - 7 October 2016) [+].
July 18, 2016
Events: 67th Annual Meeting of ISE (The Hague, The Netherlands, 21 - 26 August 2016) [+].
» Previous news [+]
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